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Home/Hormones/Progesterone

Progesterone

Your estrogen’s partner: one capsule at bedtime to keep your treatment balanced.

  • For women who still have a uterus
  • Taken at bedtime
  • Strength set by your provider
Starting at $66.33/moBilled $199 every 3 months · Recommended · 3-month supply (100 mg) (or $99 monthly)

Card authorized at checkout. Charged only if a provider approves.

Payment optionsApple PayKlarnaAffirmKlarna and Affirm on eligible orders over $300

Product images are for illustration only. Actual packaging may vary.

Progesterone is a prescription drug used with estrogen therapy to protect the uterine lining in women who have a uterus. It can cause drowsiness or dizziness, so take it at bedtime. Some progesterone capsules contain peanut oil. See Important Safety Information.

Quick questions

The short version.

What is Progesterone?

An oral progesterone capsule taken at bedtime alongside estrogen therapy.

What makes Progesterone different?

It protects the uterine lining from the effects of estrogen, which is why women who have a uterus take it with estrogen therapy.

How much does Progesterone cost?

Starting at $66.33/mo with the 3-month supply ($199 billed every 3 months), or $99 monthly. No membership fee.

How it works

Three simple
steps.

01

Get prescribed

Complete a secure online visit, and a licensed provider reviews your health history.

02

Take it at bedtime

Take one capsule by mouth at bedtime, as your provider directs.

03

Check in

Your provider follows your progress and adjusts your plan if needed.

How to get it

From your phone
to your door.

Your card is authorized at checkout, but you are only charged if a provider approves your treatment.

Today

Complete a short online visit with a few health questions

Usually within 24 hours

Hear from your provider

Free, discreet shipping

Most orders arrive within a few business days of approval, with tracking sent when your order ships

Then

Begin treatment, with your care team a message away

Compare your options

Find the
right fit.

Your provider confirms which option is appropriate for you.

TreatmentWhat it isPrice
Estradiol Patch FeaturedEstradiol · weekly skin patchStarting at $109.67/moBilled $329 every 3 months · Recommended · 3-month supply (or $133 monthly)
Estradiol PillEstradiol · daily tabletStarting at $59.67/moBilled $179 every 3 months · Recommended · 3-month supply (or $99 monthly)
Estradiol CreamCompounded estradiol · daily skin creamStarting at $66.33/moBilled $199 every 3 months · Recommended · 3-month supply (or $110 monthly)
Vaginal Estradiol CreamEstradiol 0.1 mg/g · vaginal cream with applicatorStarting at $63/moBilled $189 every 3 months · Recommended · 3-month supply (or $110 monthly)
ProgesteroneProgesterone · capsule at bedtimeStarting at $66.33/moBilled $199 every 3 months · Recommended · 3-month supply (100 mg) (or $99 monthly)
FAQs

Questions, answered.

Why do I need it?

If you have a uterus, estrogen alone can thicken its lining. Progesterone protects it.

Why at bedtime?

It can make you sleepy or dizzy.

I've had a hysterectomy. Do I need it?

Usually not. Your provider will decide.

Do I need a prescription?

Yes. Complete a short online visit to see if this treatment is right for you. A licensed provider reviews your answers and decides whether it's appropriate to prescribe.

Who makes the treatment decision?

Licensed providers make all consultation and prescribing decisions. Purchasing does not guarantee a prescription. Prescriptions are issued only after a licensed provider reviews your information and determines that treatment is appropriate.

Research & references

What the research says.

The studies discussed here may involve different formulations, doses, delivery methods, or patient populations from the treatment offered. They do not establish the safety or effectiveness of this specific compounded product. Compounded medications are not FDA-approved; FDA does not review their safety, effectiveness, or quality before marketing.

The 2022 hormone therapy position statement of The North American Menopause Society.

What was studied. A professional evidence synthesis (not a single trial) of menopausal hormone therapy.

What researchers found. Menopausal hormone therapy is the most effective treatment for hot flashes and night sweats. Low-dose vaginal estrogen is an established treatment option for menopause-related vaginal dryness and discomfort when nonprescription measures are insufficient.

How it relates to this treatment. Your clinician reviews your symptoms, medical history, and individual risks to determine whether treatment is appropriate. Patients with a uterus generally need endometrial protection (progesterone) when using systemic estrogen. Bundles combine individual treatments; the bundles themselves have not been studied as products.

“The 2022 hormone therapy position statement of The North American Menopause Society.” Menopause, 2022. PMID: 35797481.

Important Safety Information

What to know before starting Progesterone.

Progesterone is a prescription drug used with estrogen therapy to protect the uterine lining in women who have a uterus. It can cause drowsiness or dizziness, so take it at bedtime. Some progesterone capsules contain peanut oil.

We serve patients in 46 states. We do not currently provide services in Alaska, Mississippi, New Jersey or Texas. Availability can vary by product, depending on whether the dispensing pharmacy is licensed to ship to your state.

Licensed providers make all consultation and prescribing decisions. Purchasing does not guarantee a prescription. Prescriptions are issued only after a licensed provider reviews your information and determines that treatment is appropriate. Your card is authorized at checkout, but you are only charged if a provider approves your treatment.