Skin Care (GHK-Cu Peptide Skin Complex, Skin Renewal Complex)
What are these products?
The GHK-Cu Peptide Skin Complex contains GHK-Cu, a copper peptide. The Skin Renewal Complex contains estriol, a mild estrogen, and tretinoin, a prescription retinoid. Both are compounded medications. Compounded medications may be prescribed under federal law, but they are not FDA-approved, and the FDA does not review them for safety, effectiveness or manufacturing quality.
Who should not use them?
- Do not use the Skin Renewal Complex if you’re pregnant, trying to get pregnant or breastfeeding, or if you have a history of breast cancer or another estrogen-sensitive condition.
- Do not use the GHK-Cu Peptide Skin Complex if you’re allergic to copper.
- Do not apply either product to broken, irritated or sunburned skin.
- Do not use either product if you’re allergic to any of its ingredients.
How should I use them?
- Patch test on a small area first.
- Apply a thin layer to clean, dry skin as your provider directs. Use the Skin Renewal Complex at night.
- Avoid your eyes, lips and the corners of your nose.
- Wear sunscreen every day, and limit sun exposure.
What should I tell my provider first?
Tell your provider about all skin products you use, especially other retinoids, exfoliating acids, benzoyl peroxide or products that dry the skin. Tell your provider if you have eczema or sensitive skin, or are pregnant, planning a pregnancy or breastfeeding.
What are the most serious side effects?
Stop using the product and contact your care team if you have severe redness, swelling, blistering, burning or crusting. If you have a medical emergency, call 911. Get help right away for signs of an allergic reaction, such as swelling of the face, lips or throat, or trouble breathing.
What are the most common side effects?
Redness, dryness, peeling, stinging and sun sensitivity, especially in the first few weeks with tretinoin. Copper peptide can cause mild redness or irritation.
Other important information
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
This summary provides basic information about these products but does not include everything known about them. Your ReformedRx provider can answer any questions about side effects before you start treatment. Please also read the information that comes with your prescription each time it’s filled.